Product Name :
PELP1 Recombinant Rabbit Monoclonal Antibody [JE02-42]
Predicted band size :
120 kDa
Observed band size :
150 kDa
Synonyms:
glutamic acid- and leucine-rich protein 1 antibody HMX3 antibody MNAR antibody Modulator of non-genomic activity of estrogen receptor antibody Modulator of nongenomic activity of estrogen receptor antibody P160 antibody Pelp1 antibody PELP1 proline glutamic acid leucine rich protein 1 antibody PELP1_HUMAN antibody proline and glutamic acid rich nuclear protein antibody 展开
Function :
Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) also known as modulator of non-genomic activity of estrogen receptor (MNAR) and transcription factor HMX3 is a protein that in humans is encoded by the PELP1 gene. is a transcriptional corepressor for nuclear receptors such as glucocorticoid receptors and a coactivator for estrogen receptors. Proline-, glutamic acid-, and leucine-rich protein 1 (PELP1) is transcription coregulator and modulates functions of several hormonal receptors and transcription factors. PELP1 plays essential roles in hormonal signaling, cell cycle progression, and ribosomal biogenesis. PELP1 expression is upregulated in several cancers; its deregulation contributes to hormonal therapy resistance and metastasis; therefore, PELP1 represents a novel therapeutic target for many cancers.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human PELP1 aa 1,021-1,070 / 1,130.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P, FC, IP
Coupling :
unconjugated
Clone number:
JE02-42
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.β-Aspartylaspartic acid Chemscene Aliquot store at -20℃.EPhos Pd G4 uses Avoid repeated freeze / thaw cycles.PMID:33382660
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 120 kDa
Positive control :
SW620 cell lysate, MCF7 cell lysate, HeLa cell lysate, HEK-293 cell lysate, NIH/3T3 cell lysate, MCF7, human colon cancer tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue.