Product Name :
TLR2 Recombinant Rabbit Monoclonal Antibody [JM22-41]
Predicted band size :
Observed band size :
Synonyms:
CD282 antibody CD282 antigen antibody TIL 4 antibody TIL4 antibody TLR 2 antibody TLR2 antibody TLR2_HUMAN antibody Toll like receptor 2 antibody Toll like receptor 2 precursor antibody Toll-like receptor 2 antibody 展开
Function :
The TLR family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain.240401-09-6 Price TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes. TLR6 is highly homologous to TLR1, sharing greater than 65% sequence identity, and, like other members of TLR family, it induces NFkB signaling upon activation.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human TLR2 aa 21-588 (Extracellular).
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, FC, IF-Cell
Coupling :
unconjugated
Clone number:
JM22-41
RRID:
AB_3070621
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.2,3-Dibromophenol site Aliquot store at -20℃ or -80℃.PMID:33625629 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 90 kDa
Positive control :
Wild-type THP-1 whole cell lysate, HL-60 cell lysates.