Product Name :
XBP1 Recombinant Rabbit Monoclonal Antibody [JM10-62]
Predicted band size :
29 kDa
Observed band size :
40 kDa
Synonyms:
Tax responsive element binding protein 5 antibody Tax-responsive element-binding protein 5 antibody TREB5 antibody X box binding protein 1 antibody X box binding protein 2 antibody X-box-binding protein 1 antibody XBP 1 antibody XBP-1 antibody XBP1 antibody XBP1_HUMAN antibody 展开
Function :
X-box binding protein 1, also known as XBP1, is a protein which in humans is encoded by the XBP1 gene. The XBP1 protein is a transcription factor that regulates the expression of genes important to the proper functioning of the immune system and in the cellular stress response. It was first identified by its ability to bind to the Xbox, a conserved transcriptional element in the promoter of the human leukocyte antigen (HLA) DR alpha. Abnormalities in XBP1 lead to a heightened ER stress and subsequently causes a heightened susceptibility for inflammatory processes that may contribute to Alzheimer’s disease. In the colon, XBP1 anomalies have been linked to Crohn’s disease.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human XBP1 aa 126-175 / 261.
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P, IF-Cell, IF-Tissue, FC
Coupling :
unconjugated
Clone number:
JM10-62
RRID:
AB_3070380
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.170097-87-7 uses Aliquot store at -20℃ or -80℃.1,1-Diethoxy-3-phenylpropan-2-one Chemscene Avoid repeated freeze / thaw cycles.PMID:33586545
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 29 kDa
Positive control :
293T cell lysate, HepG2 cell lysate, Hela, HepG2, SW480, human colon carcinoma tissue, mouse liver tissue, 293T.