Product Name :
p21 ARC Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Actin related protein 2/3 complex subunit 3 antibody ARC21 antibody ARP2/3 complex 21 kDa subunit antibody ARP2/3 protein complex subunit p21 antibody ARPC3 antibody
Function :
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (. The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA . The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) .Buy7-Bromo-4-chloroquinolin-3-amine
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within human p21 ARC aa 120-178.N-Cyano-2-pyridinecarboximidamide Price
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3071105
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.PMID:33730923 4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
21 kDa
Positive control :
THP-1 cell lysate, rat lung tissue lysate, mouse lung tissue lysate, rat brain tissue, human colon tissue, HUVEC cell lysate.