Product Name :
2-Amino-4-phenylthiazole (CAS 2010-06-2)

Synonym :
4-Phenyl-1,3-thiazol-2-amine

Application :
2-Amino-4-phenylthiazole is used to synthesize ketone histone deacetylase inhibitors with antitumor activity

CAS:
2010-06-2

Purity:

Molecular Weight:
176.24

Formula :
C9H8N2S

Physical state:
Solid

solubility :

Shipping Condition :
Store at room temperature

Melting point:
149-153° C (lit.Tributyl(1-ethoxyethenyl)stannane manufacturer )

SMILES:
NC1=NC(=CS1)C1=CC=CC=C1

References:
:Complexes of ruthenium(III) with some 2-aminothiazole derivatives/synthesis, properties and pharmacological studies. | Nikolova, A., et al. 2004. Arzneimittelforschung. 54: 323-9. PMID: 152816185-Methyl-2-[3-(4-phenylthiazol-2-yl)triazenyl]benzenesulfonic acid as a chromogenic reagent of N-cetylpyridinium chloride Synthesis, mechanism and analytical application. | He, XL., et al. 2008. Talanta. 74: 821-30. PMID: 18371715Hit-to-lead optimization of a series of carboxamides of ethyl 2-amino-4-phenylthiazole-5-carboxylates as novel adenosine A2A receptor antagonists. | Sams, AG., et al. 2010. Bioorg Med Chem Lett. 20: 5241-4. PMID: 20659802[Design, synthesis and evaluation of new acetylcholinesterase inhibitors]. | Ma, ZY., et al. 2014. Yao Xue Xue Bao. 49: 346-51. PMID: 24961105Functional and structural characterization of 2-amino-4-phenylthiazole inhibitors of the HIV-1 nucleocapsid protein with antiviral activity.(S)-2-Methoxy-1-phenylethan-1-amine uses | Mori, M.PMID:33417197 , et al. 2014. ACS Chem Biol. 9: 1950-5. PMID: 24988251Synthesis, spectroscopic properties, molecular docking, anti-colon cancer and anti-microbial studies of some novel metal complexes for 2-amino-4-phenylthiazole derivative. | Al-Harbi, SA., et al. 2015. Spectrochim Acta A Mol Biomol Spectrosc. 145: 425-439. PMID: 25796013Development of 2-amino-4-phenylthiazole analogues to disrupt myeloid differentiation factor 88 and prevent inflammatory responses in acute lung injury. | Chen, L., et al. 2019. Eur J Med Chem. 161: 22-38. PMID: 30342423Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein. | Mori, M., et al. 2019. ACS Med Chem Lett. 10: 463-468. PMID: 30996780Comparative data on corrosion protection of mild steel in HCl using two new thiazoles. | Alamiery, A., et al. 2022. Data Brief. 40: 107838. PMID: 35106341Potential antineoplastics. II. 1-Thiocarbamoyl-3-methyl 4-arylhydrazono-2-pyrazolin-5-ones, 2-amino-4-phenyl-5-arylazothiazoles, and N-phenyl-N′-2(4-phenyl-5-arylazothiazolyl) thiocarbamides. | Garg, HG. and Sharma, RA. 1970. J Pharm Sci. 59: 348-53. PMID: 5416177Simultaneous programmed temperature GLC assay of phenol, chloroxylenol, and lidocaine hydrochloride in topical antiseptic cream. | Palermo, PJ. and Lundberg, JB. 1978. J Pharm Sci. 67: 1627-9. PMID: 712606Dyeing performance of disperse dyes based on 2-aminothiazole for cellulose triacetate and nylon fibers | Hari Raghav Maradiya & Vithal Soma Patel. 2002. Fibers and Polymers. 3: 43–48.Electrocopolymerization of a binary mixture of pyrrole and 2-amino-4-phenylthiazole: Kinetic studies, copolymer structure, and applications as corrosion protection for mild steel in acid medium | S. M. Sayyah,M. M. El-Deeb. 2007. Journal of applied polymer science. 103: 4047-4058.