Product Name :
2′-O-Methylinosine (CAS 3881-21-8)
Synonym :
2′-O-Methyl-D-inosine
Application :
CAS:
3881-21-8
Purity:
Molecular Weight:
282.25
Formula :
C11H14N4O5
Physical state:
Solid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
237.44° C (Predicted)
SMILES:
CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2NC=NC3=O)CO)O
References:
:Antiviral amphipathic oligo- and polyribonucleotides: analogue development and biological studies. | Hyde, RM., et al. 2003. J Med Chem. 46: 1878-85. PMID: 12723951A novel nucleoside hydrolase from Lactobacillus buchneri LBK78 catalyzing hydrolysis of 2′-O-methylribonucleosides. | Mitsukawa, Y., et al. 2016. Biosci Biotechnol Biochem. 80: 1568-76. PMID: 27180876Highly efficient chemical synthesis of 2′-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases. | Sproat, BS., et al. 1989. Nucleic Acids Res. 17: 3373-86. PMID: 2726482Enzymatic synthesis of 2′-O-methylribonucleosides with a nucleoside hydrolase family enzyme from Lactobacillus buchneri LBK78. | Mitsukawa, Y., et al. 2017. J Biosci Bioeng. 123: 659-664. PMID: 28202305New nucleoside hydrolase with transribosylation activity from Agromyces sp. MM-1 and its application for enzymatic synthesis of 2′-O-methylribonucleosides. | Mitsukawa, Y., et al. 2018. J Biosci Bioeng. 125: 38-45. PMID: 28826816Development of a highly sensitive method for the quantitative analysis of modified nucleosides using UHPLC-UniSpray-MS/MS. | Kogaki, T., et al. 2021. J Pharm Biomed Anal. 197: 113943. PMID: 33601155Inosine and its methyl derivatives: Occurrence, biogenesis, and function in RNA.1,2,5-Oxadiazole-3,4-diamine custom synthesis | Dutta, N., et al. 2022. Prog Biophys Mol Biol. 169-170: 21-52. PMID: 35065168Identification of Inosine and 2′-O-Methylinosine Modifications in Yeast Messenger RNA by Liquid Chromatography-Tandem Mass Spectrometry Analysis.98642-15-0 uses | Feng, YJ.PMID:33602019 , et al. 2022. Anal Chem. 94: 4747-4755. PMID: 35266699Potential Misidentification of Natural Isomers and Mass-Analogs of Modified Nucleosides by Liquid Chromatography-Triple Quadrupole Mass Spectrometry. | Lin, X., et al. 2022. Genes (Basel). 13: PMID: 35627263Unravelling Strain-Specific Modifications of Toxoplasma gondii tRNA and sncRNA Using LC-MS/MS. | Wang, W., et al. 2023. Microbiol Spectr. e0356422. PMID: 37036375Influence of 2′-O-alkylation on the structure of single-stranded polynucleotides and the stability of 2′-O-alkylated polynucleotide complexes. | Rottman, F., et al. 1974. Biochemistry. 13: 2762-71. PMID: 4847544Naturally occurring 2′-O-methylpurine nucleosides with hypotensive properties. | Yamada, T., et al. 1998. Cell Mol Life Sci. 54: 125-8. PMID: 9539952Isolation and identification of apoptosis inducing nucleosides from CD57(+)HLA-DRbright natural suppressor cell line. | Mori, T., et al. 1998. Biochem Biophys Res Commun. 251: 416-22. PMID: 9792789